There plenty of different workflows. I do see lots of overlap between web browser usage. Some use the same tab for everything. Some want a new tab for everything the click on. Some have multiple profiles with default tabs set. Some use tab stacks. Some want clean slate on lauch. Some want to restore the old session. Some user horizontal tabs, so use vertical tabs. Some have big history, others clean that regularly. Some save the whole download history, some want it clean. Some use tiled windows, some don't. Note: kind of addicted to Vivaldi browser (Chromium based, as Edge/Chromium/Brave and so on) where you have plenty of options to make it your own.
But anyhow, I have a database for linguistic purposes.
I have databases for (continental law) annotations. So I can add notes/comments insight related to every law there is
I have some interest in the Stock Market so keep notes about company's or derivate products which have my interest. (different database
I read certain articles in papers which have I want to save. Different database.
I have databases about allergy's and intolerances. Keeping track of different sites (stored bookmark notes). And making additional notes being able to keeping structure in it. It also makes it easier to share.
I have number of scientific papers I want to store. So I'm using MyInfo as (Zotero/Mendely) kind of app
& You can use it as evidence database. So collection of all proof (documents, photo's).
Works for advocates.
But probably also for detective of journalistic purposes. (Also different databases)
It works for people who have to store tremendous amount of manuals (say of Kitchen appliances); So you're small repair company.
I also use MyInfo kind of password manager (again separate database). For the common used, not very interesting webshop logins

. If this wise to do, we can argue about. But well Nirsoft is able to recover plenty of those. Clipboard content can be intercepted anyhow. And typing password.. well keyloggers. Maybe it's possible to intercept wireless keyboards too. So the whole security is relative anyhow. And there are enough people using the same password over and over. I have variety out of security concerns. And I can't remember > 100 generated passwords with 8-12 characters (including special symbols and such). If those are save is topic to, reminders me a comic saying generated passwords being hard to remember for people but easy to guess for computers. 2-Step Verification will be norm soon. Even for webshops at some point.
It's possible scrivener alternative (for Writers)
A user here uses 1500 sections for managing building descriptions (and documentation) in single database.
So more matter of what works for you. But having items 'sorted' on topic makes it easier. (I use the pinned notebook panel) And notebook with 1500 notebooks of all sorts of topics is pretty overwhelming. But for the user with 1500 simply makes sense, all those sections are about the 'same topic'. Except different buildings (estate agent or architect).
Another concern is database size. My databases tend to expand. But like to keep within proportions. Say around 400 MB each. Which requires me to split.
Again this is Swiss Knife. You develop you're own style within you're own use cases. And takes what works for you best. And same time trying too look at what design issues. Which would make MyInfo even more flexible to fit in any workflow, in business cases or for private use.
MyInfo is already great, but can be become even better. Have put forward enough ideas to fill the development for the next 5-7 years. I want to go more or less the route where SeaMonkey failed. So plenty of 'simple tools' in one. Not specialized tool for ever stupid element. MyInfo should handle mail and calendar as (EssentialPIM) does. And having some basic brain storming tools (Scapple alike; not mindmap craze with lots of colorful toys something simple.
I really don't want to tike about box border size & color &fill color and position to much. It's really distracting. But well those fancy toy like programs look nice. And it would mean that a program is done at some point (but if you're company living form revenue you have to create more features to make upgrade worth it).